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Yibin Wang, Ph.D. [ Edit Your Profile ]

Work Email Address: yibinwang@mednet.ucla.edu
Work Email Address: ywangibi@ucla.edu

Work Phone Number: (310) 206-5197

Mailing Address:
UCLA, David Geffen School of Medicine
Department of Anesthesiology
Division of Molecular Medicine
650 Charles E Young Dr.
CHS/BH569
Los Angeles, CA 90095

Work Address:
CHS BH-569
Campus - 711520
CA

Work
Position/Title
Vice-Chair, Research, and Professor, Anesthesiology
Professor, Medicine
Member, California NanoSystems Institute, Cell & Developmental Biology GPB Home Area, Center for Duchenne Muscular Dystrophy, Genetics & Genomics GPB Home Area, JCCC Signal Transduction and Therapeutics Program Area, Molecular, Cellular & Integrative Physiology GPB Home Area, themes
Faculty, Cardiovascular Research Laboratory, Cardiology

Education:
Degrees:
Ph.D., Baylor College of Medicine, 1993
B.S., New York State University, 1988

Publications
Touma, M.; Kang, X.; Zhao, Y.; Cass, A. A.; Gao, F.; Biniwale, R.; Coppola, G.; Xiao, X.; Reemtsen, B.; Wang, Y., Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery. Circ Cardiovasc Genet. 2016; 9(5): 395-407.
Wang, J. J.; Rau, C.; Avetisyan, R.; Ren, S.; Romay, M. C.; Stolin, G.; Gong, K. W.; Wang, Y.; Lusis, A. J., Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. PLoS Genet. 2016; 12(7): e1006038.
Gao, C.; Wang, Y., Positive Role for a Negative Calcineurin Regulator in Cardiac Hypertrophy. Hypertension. 2016; 67(5): 841-2.
Gao, C.; Ren, S.; Lee, J. H.; Qiu, J.; Chapski, D. J.; Rau, C. D.; Zhou, Y.; Abdellatif, M.; Nakano, A.; Vondriska, T. M.; Xiao, X.; Fu, X. D.; Chen, J. N.; Wang, Y., RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure. J Clin Invest. 2016; 126(1): 195-206.
Lusis, A. J.; Seldin, M. M.; Allayee, H.; Bennett, B. J.; Civelek, M.; Davis, R. C.; Eskin, E.; Farber, C. R.; Hui, S.; Mehrabian, M.; Norheim, F.; Pan, C.; Parks, B.; Rau, C. D.; Smith, D. J.; Vallim, T.; Wang, Y.; Wang, J., The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits. J Lipid Res. 2016; 57(6): 925-42.
Wang, Z.; Zhang, X. J.; Ji, Y. X.; Zhang, P.; Deng, K. Q.; Gong, J.; Ren, S.; Wang, X.; Chen, I.; Wang, H.; Gao, C.; Yokota, T.; Ang, Y. S.; Li, S.; Cass, A.; Vondriska, T. M.; Li, G.; Deb, A.; Srivastava, D.; Yang, H. T.; Xiao, X.; Li, H.; Wang, Y., The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy. Nat Med. 2016; 22(10): 1131-1139.
Song, Y.; Zhang, Y.; Jiang, H.; Zhu, Y.; Liu, L.; Feng, W.; Yang, L.; Wang, Y.; Li, M., Activation of Notch3 promotes pulmonary arterial smooth muscle cells proliferation via Hes1/p27Kip1 signaling pathway. FEBS Open Bio. 2015; 5: 656-60.
Rau, C. D.; Lusis, A. J.; Wang, Y., Genetics of common forms of heart failure: challenges and potential solutions. Curr Opin Cardiol. 2015; 30(3): 222-7.
Rau, C. D.; Parks, B.; Wang, Y.; Eskin, E.; Simecek, P.; Churchill, G. A.; Lusis, A. J., High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. G3 (Bethesda). 2015; 5(10): 2021-6.
Cai, R.; Gu, J.; Sun, H.; Liu, X.; Mei, W.; Qi, Y.; Xue, S.; Ren, S.; Rabinowitz, J. E.; Wang, Y.; Yeh, E. T.; Cheng, J., Induction of SENP1 in myocardium contributes to abnormities of mitochondria and cardiomyopathy. J Mol Cell Cardiol. 2015; 79: 115-22.
Feng, J.; Gong, D.; Fu, X.; Wu, T. T.; Wang, J.; Chang, J.; Zhou, J.; Lu, G.; Wang, Y.; Sun, R., M1 of Murine Gamma-Herpesvirus 68 Induces Endoplasmic Reticulum Chaperone Production. Sci Rep. 2015; 5: 17228.
Rau, C. D.; Wang, J.; Avetisyan, R.; Romay, M. C.; Martin, L.; Ren, S.; Wang, Y.; Lusis, A. J., Mapping genetic contributions to cardiac pathology induced by Beta-adrenergic stimulation in mice. Circ Cardiovasc Genet. 2015; 8(1): 40-9.
Neelankavil, J.; Rau, C. D.; Wang, Y., The Genetic Basis of Coronary Artery Disease and Atrial Fibrillation: A Search for Disease Mechanisms and Therapeutic Targets. J Cardiothorac Vasc Anesth. 2015; 29(5): 1328-32.
Ren, S.; Lu, G.; Ota, A.; Zhou, Z. H.; Vondriska, T. M.; Lane, T. F.; Wang, Y., IRE1 phosphatase PP2Ce regulates adaptive ER stress response in the postpartum mammary gland. PLoS One. 2014; 9(11): e111606.
Sun, H.; Wang, Y., Interferon regulatory factors in heart: stress response beyond inflammation. Hypertension. 2014; 63(4): 663-4.
Lam, M. P.; Wang, D.; Lau, E.; Liem, D. A.; Kim, A. K.; Ng, D. C.; Liang, X.; Bleakley, B. J.; Liu, C.; Tabaraki, J. D.; Cadeiras, M.; Wang, Y.; Deng, M. C.; Ping, P., Protein kinetic signatures of the remodeling heart following isoproterenol stimulation. J Clin Invest. 2014; 124(4): 1734-44.
Gao, C.; Wang, Y., Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome. Circ J. 2014; 78(5): 1038-47.
Gupta, A.; Rohlfsen, C.; Leppo, M. K.; Chacko, V. P.; Wang, Y.; Steenbergen, C.; Weiss, R. G., Creatine kinase-overexpression improves myocardial energetics, contractile dysfunction and survival in murine doxorubicin cardiotoxicity. PLoS One. 2013; 8(10): e74675.
Foster, W. H.; Langenbacher, A.; Gao, C.; Chen, J.; Wang, Y., Nuclear phosphatase PPM1G in cellular survival and neural development. Dev Dyn. 2013; 242(9): 1101-9.
Lu, G.; Ota, A.; Ren, S.; Franklin, S.; Rau, C. D.; Ping, P.; Lane, T. F.; Zhou, Z. H.; Reue, K.; Lusis, A. J.; Vondriska, T.; Wang, Y., PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response. Mol Metab. 2013; 2(4): 405-16.
Li, J.; Umar, S.; Iorga, A.; Youn, J. Y.; Wang, Y.; Regitz-Zagrosek, V.; Cai, H.; Eghbali, M., Cardiac vulnerability to ischemia/reperfusion injury drastically increases in late pregnancy. Basic Res Cardiol. 2012; 107(4): 271.
Gao, C.; Wang, Y., Global impact of RNA splicing on transcriptome remodeling in the heart. J Zhejiang Univ Sci B. 2012; 13(8): 603-8.
Ghazalpour, A.; Rau, C. D.; Farber, C. R.; Bennett, B. J.; Orozco, L. D.; van Nas, A.; Pan, C.; Allayee, H.; Beaven, S. W.; Civelek, M.; Davis, R. C.; Drake, T. A.; Friedman, R. A.; Furlotte, N.; Hui, S. T.; Jentsch, J. D.; Kostem, E.; Kang, H. M.; Kang, E. Y.; Joo, J. W.; Korshunov, V. A.; Laughlin, R. E.; Martin, L. J.; Ohmen, J. D.; Parks, B. W.; Pellegrini, M.; Reue, K.; Smith, D. J.; Tetradis, S.; Wang, J.; Wang, Y.; Weiss, J. N.; Kirchgessner, T.; Gargalovic, P. S.; Eskin, E.; Lusis, A. J.; LeBoeuf, R. C., Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome. 2012; 23(9-10): 680-92.
Sun, H.; Wang, Y., Novel Ser/Thr protein phosphatases in cell death regulation. Physiology (Bethesda). 2012; 27(1): 43-52.
Franklin, S.; Chen, H.; Mitchell-Jordan, S.; Ren, S.; Wang, Y.; Vondriska, T. M., Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth. Mol Cell Proteomics. 2012; 11(6): M111 014258.
MacLellan, W. R.; Wang, Y.; Lusis, A. J., Systems-based approaches to cardiovascular disease. Nat Rev Cardiol. 2012; 9(3): 172-84.
Foster, W. H.; Tidball, J. G.; Wang, Y., p38gamma activity is required for maintenance of slow skeletal muscle size. Muscle Nerve. 2012; 45(2): 266-73.
Sun, H.; Lu, G.; Ren, S.; Chen, J.; Wang, Y., Catabolism of branched-chain amino acids in heart failure: insights from genetic models. Pediatr Cardiol. 2011; 32(3): 305-10.
Deng, N.; Zhang, J.; Zong, C.; Wang, Y.; Lu, H.; Yang, P.; Wang, W.; Young, G. W.; Wang, Y.; Korge, P.; Lotz, C.; Doran, P.; Liem, D. A.; Apweiler, R.; Weiss, J. N.; Duan, H.; Ping, P., Phosphoproteome analysis reveals regulatory sites in major pathways of cardiac mitochondria. Mol Cell Proteomics. 2011; 10(2): M110 000117.
Marber, M. S.; Rose, B.; Wang, Y., The p38 mitogen-activated protein kinase pathway--a potential target for intervention in infarction, hypertrophy, and heart failure. J Mol Cell Cardiol. 2011; 51(4): 485-90.
Streicher, J. M.; Kamei, K.; Ishikawa, T. O.; Herschman, H.; Wang, Y., Compensatory hypertrophy induced by ventricular cardiomyocyte-specific COX-2 expression in mice. J Mol Cell Cardiol. 2010; 49(1): 88-94.
Otsuka, M.; Kang, Y. J.; Ren, J.; Jiang, H.; Wang, Y.; Omata, M.; Han, J., Distinct effects of p38alpha deletion in myeloid lineage and gut epithelia in mouse models of inflammatory bowel disease. Gastroenterology. 2010; 138(4): 1255-65, 1265 e1-9.
Rose, B. A.; Force, T.; Wang, Y., Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. Physiol Rev. 2010; 90(4): 1507-46.
Ahuja, P.; Zhao, P.; Angelis, E.; Ruan, H.; Korge, P.; Olson, A.; Wang, Y.; Jin, E. S.; Jeffrey, F. M.; Portman, M.; Maclellan, W. R., Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice. J Clin Invest. 2010; 120(5): 1494-505.
Paulsson, A. K.; Franklin, S.; Mitchell-Jordan, S. A.; Ren, S.; Wang, Y.; Vondriska, T. M., Post-translational regulation of calsarcin-1 during pressure overload-induced cardiac hypertrophy. J Mol Cell Cardiol. 2010; 48(6): 1206-14.
Papanicolaou, K. N.; Streicher, J. M.; Ishikawa, T. O.; Herschman, H.; Wang, Y.; Walsh, K., Preserved heart function and maintained response to cardiac stresses in a genetic model of cardiomyocyte-targeted deficiency of cyclooxygenase-2. J Mol Cell Cardiol. 2010; 49(2): 196-209.
Cross, H. R.; Li, M.; Petrich, B. G.; Murphy, E.; Wang, Y.; Steenbergen, C., Effect of p38 MAP kinases on contractility and ischemic injury in intact heart. Acta Physiol Hung. 2009; 96(3): 307-23.
Lu, G.; Sun, H.; Korge, P.; Koehler, C. M.; Weiss, J. N.; Wang, Y., Functional characterization of a mitochondrial Ser/Thr protein phosphatase in cell death regulation. Methods Enzymol. 2009; 457: 255-73.
Ruan, H.; Li, J.; Ren, S.; Gao, J.; Li, G.; Kim, R.; Wu, H.; Wang, Y., Inducible and cardiac specific PTEN inactivation protects ischemia/reperfusion injury. J Mol Cell Cardiol. 2009; 46(2): 193-200.
Seimon, T. A.; Wang, Y.; Han, S.; Senokuchi, T.; Schrijvers, D. M.; Kuriakose, G.; Tall, A. R.; Tabas, I. A., Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice. J Clin Invest. 2009; 119(4): 886-98.
Andersson, K. B.; Finsen, A. V.; Sjaland, C.; Winer, L. H.; Sjaastad, I.; Odegaard, A.; Louch, W. E.; Wang, Y.; Chen, J.; Chien, K. R.; Sejersted, O. M.; Christensen, G., Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models. Cell Calcium. 2009; 46(3): 219-25.
Andersson, K. B.; Birkeland, J. A.; Finsen, A. V.; Louch, W. E.; Sjaastad, I.; Wang, Y.; Chen, J.; Molkentin, J. D.; Chien, K. R.; Sejersted, O. M.; Christensen, G., Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene. J Mol Cell Cardiol. 2009; 47(2): 180-7.
Lu, G.; Sun, H.; She, P.; Youn, J. Y.; Warburton, S.; Ping, P.; Vondriska, T. M.; Cai, H.; Lynch, C. J.; Wang, Y., Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells. J Clin Invest. 2009; 119(6): 1678-87.
Lu, G.; Wang, Y., Functional diversity of mammalian type 2C protein phosphatase isoforms: new tales from an old family. Clin Exp Pharmacol Physiol. 2008; 35(2): 107-12.
Streicher, J. M.; Wang, Y., The role of COX-2 in heart pathology. Cardiovasc Hematol Agents Med Chem. 2008; 6(1): 69-79.
Nguyen, C. T.; Lu, Q.; Wang, Y.; Chen, J. N., Zebrafish as a model for cardiovascular development and disease. Drug Discov Today Dis Models. 2008; 5(3): 135-140.
Peter, P. S.; Brady, J. E.; Yan, L.; Chen, W.; Engelhardt, S.; Wang, Y.; Sadoshima, J.; Vatner, S. F.; Vatner, D. E., Inhibition of p38 alpha MAPK rescues cardiomyopathy induced by overexpressed beta 2-adrenergic receptor, but not beta 1-adrenergic receptor. J Clin Invest. 2007; 117(5): 1335-43.
Ursitti, J. A.; Petrich, B. G.; Lee, P. C.; Resneck, W. G.; Ye, X.; Yang, J.; Randall, W. R.; Bloch, R. J.; Wang, Y., Role of an alternatively spliced form of alphaII-spectrin in localization of connexin 43 in cardiomyocytes and regulation by stress-activated protein kinase. J Mol Cell Cardiol. 2007; 42(3): 572-81.
Eghbali, M.; Wang, Y.; Toro, L.; Stefani, E., Heart hypertrophy during pregnancy: a better functioning heart?. Trends Cardiovasc Med. 2006; 16(8): 285-91.
Glaser, N. D.; Lukyanenko, Y. O.; Wang, Y.; Wilson, G. M.; Rogers, T. B., JNK activation decreases PP2A regulatory subunit B56alpha expression and mRNA stability and increases AUF1 expression in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2006; 291(3): H1183-92.
Liu, J.; Sadoshima, J.; Zhai, P.; Hong, C.; Yang, G.; Chen, W.; Yan, L.; Wang, Y.; Vatner, S. F.; Vatner, D. E., Pressure overload induces greater hypertrophy and mortality in female mice with p38alpha MAPK inhibition. J Mol Cell Cardiol. 2006; 41(4): 680-8.
Rehan, V. K.; Wang, Y.; Patel, S.; Santos, J.; Torday, J. S., Rosiglitazone, a peroxisome proliferator-activated receptor-gamma agonist, prevents hyperoxia-induced neonatal rat lung injury in vivo. Pediatr Pulmonol. 2006; 41(6): 558-69.
Takimoto, E.; Champion, H. C.; Li, M.; Belardi, D.; Ren, S.; Rodriguez, E. R.; Bedja, D.; Gabrielson, K. L.; Wang, Y.; Kass, D. A., Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy. Nat Med. 2005; 11(2): 214-22.
Wang, G.; Liem, D. A.; Vondriska, T. M.; Honda, H. M.; Korge, P.; Pantaleon, D. M.; Qiao, X.; Wang, Y.; Weiss, J. N.; Ping, P., Nitric oxide donors protect murine myocardium against infarction via modulation of mitochondrial permeability transition. Am J Physiol Heart Circ Physiol. 2005; 288(3): H1290-5.
Takimoto, E.; Champion, H. C.; Li, M.; Ren, S.; Rodriguez, E. R.; Tavazzi, B.; Lazzarino, G.; Paolocci, N.; Gabrielson, K. L.; Wang, Y.; Kass, D. A., Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load. J Clin Invest. 2005; 115(5): 1221-31.
Ren, J.; Zhang, S.; Kovacs, A.; Wang, Y.; Muslin, A. J., Role of p38alpha MAPK in cardiac apoptosis and remodeling after myocardial infarction. J Mol Cell Cardiol. 2005; 38(4): 617-23.
Zhang, L.; Zhu, H.; Davis, J. J.; Jacob, D.; Wu, S.; Teraishi, F.; Gutierrez, A.; Wang, Y.; Fang, B., Lack of p38 MAP kinase activation in TRAIL-resistant cells is not related to the resistance to TRAIL-mediated cell death. Cancer Biol Ther. 2004; 3(3): 296-301.
Zheng, M.; Dilly, K.; Dos Santos Cruz, J.; Li, M.; Gu, Y.; Ursitti, J. A.; Chen, J.; Ross, J., Jr.; Chien, K. R.; Lederer, J. W.; Wang, Y., Sarcoplasmic reticulum calcium defect in Ras-induced hypertrophic cardiomyopathy heart. Am J Physiol Heart Circ Physiol. 2004; 286(1): H424-33.
Petrich, B. G.; Wang, Y., Stress-activated MAP kinases in cardiac remodeling and heart failure; new insights from transgenic studies. Trends Cardiovasc Med. 2004; 14(2): 50-5.
Minamisawa, S.; Wang, Y.; Chen, J.; Ishikawa, Y.; Chien, K. R.; Matsuoka, R., Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling. J Biol Chem. 2003; 278(11): 9570-5..
Christensen, G.; Gruber, P. J.; Wang, Y.; Chien, K. R., Embryonic and neonatal cardiac gene transfer in vivo. Methods Mol Biol. 2003; 219: 169-78.
Domsic, J. K.; Wang, Y.; Mayeda, A.; Krainer, A. R.; Stoltzfus, C. M., Human immunodeficiency virus type 1 hnRNP A/B-dependent exonic splicing silencer ESSV antagonizes binding of U2AF65 to viral polypyrimidine tracts. Mol Cell Biol. 2003; 23(23): 8762-72.
Isoda, T.; Paolocci, N.; Haghighi, K.; Wang, C.; Wang, Y.; Georgakopoulos, D.; Servillo, G.; Della Fazia, M. A.; Kranias, E. G.; Depaoli-Roach, A. A.; Sassone-Corsi, P.; Kass, D. A., Novel regulation of cardiac force-frequency relation by CREM (cAMP response element modulator). FASEB J. 2003; 17(2): 144-51.
Petrich, B. G.; Molkentin, J. D.; Wang, Y., Temporal activation of c-Jun N-terminal kinase in adult transgenic heart via cre-loxP-mediated DNA recombination. FASEB J. 2003; 17(6): 749-51.
Zhang, S.; Weinheimer, C.; Courtois, M.; Kovacs, A.; Zhang, C. E.; Cheng, A. M.; Wang, Y.; Muslin, A. J., The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis. J Clin Invest. 2003; 111(6): 833-41.
Weiss, R. G.; Chatham, J. C.; Georgakopolous, D.; Charron, M. J.; Wallimann, T.; Kay, L.; Walzel, B.; Wang, Y.; Kass, D. A.; Gerstenblith, G.; Chacko, V. P., An increase in the myocardial PCr/ATP ratio in GLUT4 null mice. FASEB J. 2002; 16(6): 613-5.
Hoshijima, M.; Ikeda, Y.; Iwanaga, Y.; Minamisawa, S.; Date, M. O.; Gu, Y.; Iwatate, M.; Li, M.; Wang, L.; Wilson, J. M.; Wang, Y.; Ross, J., Jr.; Chien, K. R., Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery. Nat Med. 2002; 8(8): 864-71.
Sotoudeh, M.; Li, Y. S.; Yajima, N.; Chang, C. C.; Tsou, T. C.; Wang, Y.; Usami, S.; Ratcliffe, A.; Chien, S.; Shyy, J. Y., Induction of apoptosis in vascular smooth muscle cells by mechanical stretch. Am J Physiol Heart Circ Physiol. 2002; 282(5): H1709-16.
Petrich, B. G.; Liao, P.; Wang, Y., Using a gene-switch transgenic approach to dissect distinct roles of MAP kinases in heart failure. Cold Spring Harb Symp Quant Biol. 2002; 67: 429-37..
Wang, Y., Signal transduction in cardiac hypertrophy--dissecting compensatory versus pathological pathways utilizing a transgenic approach. Curr Opin Pharmacol. 2001; 1(2): 134-40.
Wang, I. I.; Huang, I. I., Adenovirus technology for gene manipulation and functional studies. Drug Discov Today. 2000; 5(1): 10-16.
Wang, X.; McGowan, C. H.; Zhao, M.; He, L.; Downey, J. S.; Fearns, C.; Wang, Y.; Huang, S.; Han, J., Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest. Mol Cell Biol. 2000; 20(13): 4543-52.
Garcia, G. E.; Xia, Y.; Chen, S.; Wang, Y.; Ye, R. D.; Harrison, J. K.; Bacon, K. B.; Zerwes, H. G.; Feng, L., NF-kappaB-dependent fractalkine induction in rat aortic endothelial cells stimulated by IL-1beta, TNF-alpha, and LPS. J Leukoc Biol. 2000; 67(4): 577-84.
Saurin, A. T.; Martin, J. L.; Heads, R. J.; Foley, C.; Mockridge, J. W.; Wright, M. J.; Wang, Y.; Marber, M. S., The role of differential activation of p38-mitogen-activated protein kinase in preconditioned ventricular myocytes. FASEB J. 2000; 14(14): 2237-46.
Luo, Z. D.; Wang, Y.; Werlen, G.; Camp, S.; Chien, K. R.; Taylor, P., Calcineurin enhances acetylcholinesterase mRNA stability during C2-C12 muscle cell differentiation. Mol Pharmacol. 1999; 56(5): 886-94.
Minamisawa, S.; Hoshijima, M.; Chu, G.; Ward, C. A.; Frank, K.; Gu, Y.; Martone, M. E.; Wang, Y.; Ross, J., Jr.; Kranias, E. G.; Giles, W. R.; Chien, K. R., Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy. Cell. 1999; 99(3): 313-22.
Fu, Y.; Wang, Y.; Evans, S. M., Viral sequences enable efficient and tissue-specific expression of transgenes in Xenopus. Nat Biotechnol. 1998; 16(3): 253-7.
Christensen, G.; Wang, Y.; Chien, K. R., Physiological assessment of complex cardiac phenotypes in genetically engineered mice. Am J Physiol. 1997; 272(6 Pt 2): H2513-24.
Lu, B.; Federoff, H. J.; Wang, Y.; Goldsmith, L. A.; Scott, G., Topical application of viral vectors for epidermal gene transfer. J Invest Dermatol. 1997; 108(5): 803-8.
Wang, Y.; Krushel, L. A.; Edelman, G. M., Targeted DNA recombination in vivo using an adenovirus carrying the cre recombinase gene. Proc Natl Acad Sci U S A. 1996; 93(9): 3932-6.
Svensson, E.; Wang, Y.; Eisensmith, R. C.; Hagenfeldt, L.; Woo, S. L., Three polymorphisms but no disease-causing mutations in the proximal part of the promoter of the phenylalanine hydroxylase gene. Eur J Hum Genet. 1993; 1(4): 306-13.
Gao Chen, Wang Yibin, Untangle a Broken Heart via Janus Kinase 1. Circulation research. 2017; 121(6): 589-590.
Touma Marlin, Kang Xuedong, Gao Fuying, Zhao Yan, Cass Ashley A, Biniwale Reshma, Xiao Xinshu, Eghbali Mansuoreh, Coppola Giovanni, Reemtsen Brian, Wang Yibin, Wnt11 regulates cardiac chamber development and disease during perinatal maturation. JCI insight. 2017; 2(17): .
Rosa-Garrido Manuel, Chapski Douglas J, Schmitt Anthony D, Kimball Todd H, Karbassi Elaheh, Monte Emma, Balderas Enrique, Pellegrini Matteo, Shih Tsai-Ting, Soehalim Elizabeth, Liem David A, Ping Peipei, Galjart Niels J, Ren Shuxun, Wang Yibin, Ren Bing, Vondriska Thomas M, High Resolution Mapping of Chromatin Conformation in Cardiac Myocytes Reveals Structural Remodeling of the Epigenome in Heart Failure. Circulation. 2017; 23(46): 11175.
Shimizu Hirohito, Langenbacher Adam D, Huang Jie, Wang Kevin, Otto Georg, Geisler Robert, Wang Yibin, Chen Jau-Nian, The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes. eLife. 2017; 6(6): 589-590.
Touma Marlin, Reemtsen Brian, Halnon Nancy, Alejos Juan, Finn J Paul, Nelson Stanley F, Wang Yibin, A Path to Implement Precision Child Health Cardiovascular Medicine. Frontiers in cardiovascular medicine. 2017; 4(4): 36.
Rose Beth A, Yokota Tomohiro, Chintalgattu Vishnu, Ren Shuxun, Iruela-Arispe Luisa, Khakoo Aarif Y, Minamisawa Susumu, Wang Yibin, Cardiac Myocyte p38α Kinase Regulates Angiogenesis via Myocyte-Endothelial Cell Cross-talk During Stress-Induced Remodeling in Heart. The Journal of biological chemistry. 2017; 21(4): 817-827.
Gao Chen, Howard-Quijano Kimberly, Rau Christoph, Takamiya Tatsuo, Song Yang, Shivkumar Kalyanam, Wang Yibin, Mahajan Aman, Inflammatory and apoptotic remodeling in autonomic nervous system following myocardial infarction. PloS one. 2017; 12(5): e0177750.
Seldin Marcus M, Kim Eric D, Romay Milagros C, Li Shen, Rau Christoph D, Wang Jessica J, Krishnan Karthickeyan Chella, Wang Yibin, Deb Arjun, Lusis Aldons J, A systems genetics approach identifies Trp53inp2 as a link between cardiomyocyte glucose utilization and hypertrophic response. American journal of physiology. Heart and circulatory physiology. 2017; 312(4): H728-H741.
Cong Qian, Jia Hao, Li Ping, Qiu Shoutao, Yeh James, Wang Yibin, Zhang Zhen-Lin, Ao Junping, Li Baojie, Liu Huijuan, p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner. Scientific reports. 2017; 7(5): 45964.
Pillai Indulekha C L, Li Shen, Romay Milagros, Lam Larry, Lu Yan, Huang Jie, Dillard Nathaniel, Zemanova Marketa, Rubbi Liudmilla, Wang Yibin, Lee Jason, Xia Ming, Liang Owen, Xie Ya-Hong, Pellegrini Matteo, Lusis Aldons J, Deb Arjun, Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification. Cell stem cell. 2017; 20(2): 218-232.e5.
Ding Yichen, Lee Juhyun, Ma Jianguo, Sung Kevin, Yokota Tomohiro, Singh Neha, Dooraghi Mojdeh, Abiri Parinaz, Wang Yibin, Kulkarni Rajan P, Nakano Atsushi, Nguyen Thao P, Fei Peng, Hsiai Tzung K, Light-sheet fluorescence imaging to localize cardiac lineage and protein distribution. Scientific reports. 2017; 7(3): 42209.
Rau Christoph D, Romay Milagros C, Tuteryan Mary, Wang Jessica J-C, Santolini Marc, Ren Shuxun, Karma Alain, Weiss James N, Wang Yibin, Lusis Aldons J, Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice. Cell systems. 2017; 4(1): 121-128.e4.
Sun Haipeng, Wang Yibin, Branched chain amino acid metabolic reprogramming in heart failure. Biochimica et biophysica acta. 2016; 1862(12): 2270-2275.
Dong Weibing, Zhou Meiyi, Dong Mei, Pan Bangfen, Liu Yunxia, Shao Jing, Gu Xiaoping, Huang Ying, Li Guangping, Wang Yibin, Sun Haipeng, Keto acid metabolites of branched-chain amino acids inhibit oxidative stress-induced necrosis and attenuate myocardial ischemia-reperfusion injury. Journal of molecular and cellular cardiology. 2016; 101(12): 90-98.
Rau, C. D.; Romay, M. C.; Tuteryan, M.; Wang, J. J.; Santolini, M.; Ren, S.; Karma, A.; Weiss, J. N.; Wang, Y.; Lusis, A. J., Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice. Cell Syst. 2016; .
Pillai, I. C.; Li, S.; Romay, M.; Lam, L.; Lu, Y.; Huang, J.; Dillard, N.; Zemanova, M.; Rubbi, L.; Wang, Y.; Lee, J.; Xia, M.; Liang, O.; Xie, Y. H.; Pellegrini, M.; Lusis, A. J.; Deb, A., Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification. Cell Stem Cell. 2016; .
Dong, W.; Zhou, M.; Dong, M.; Pan, B.; Liu, Y.; Shao, J.; Gu, X.; Huang, Y.; Li, G.; Wang, Y.; Sun, H., Keto acid metabolites of branched-chain amino acids inhibit oxidative stress-induced necrosis and attenuate myocardial ischemia-reperfusion injury. J Mol Cell Cardiol. 2016; 101: 90-98.
Franklin Sarah, Kimball Todd, Rasmussen Tara L, Rosa-Garrido Manuel, Chen Haodong, Tran Tam, Miller Mickey R, Gray Ricardo, Jiang Shanxi, Ren Shuxun, Wang Yibin, Tucker Haley O, Vondriska Thomas M, The chromatin-binding protein Smyd1 restricts adult mammalian heart growth. American journal of physiology. Heart and circulatory physiology. 2016; 311(5): H1234-H1247.
Franklin, S.; Kimball, T.; Rasmussen, T. L.; Rosa-Garrido, M.; Chen, H.; Tran, T.; Miller, M. R.; Gray, R.; Jiang, S.; Ren, S.; Wang, Y.; Tucker, H. O.; Vondriska, T. M., The chromatin-binding protein Smyd1 restricts adult mammalian heart growth. Am J Physiol Heart Circ Physiol. 2016; 311(5): H1234-H1247.
Wang, J. J.; Aboulhosn, J. A.; Hofer, I. S.; Mahajan, A.; Wang, Y.; Vondriska, T. M., Operationalizing Precision Cardiovascular Medicine: Three Innovations. Circ Res. 2016; 119(9): 984-987.
Touma Marlin, Kang Xuedong, Zhao Yan, Cass Ashley A, Gao Fuying, Biniwale Reshma, Coppola Giovanni, Xiao Xinshu, Reemtsen Brian, Wang Yibin, Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery. Circulation. Cardiovascular genetics. 2016; 9(5): 395-407.
Wang Jessica J, Aboulhosn Jamil A, Hofer Ira S, Mahajan Aman, Wang Yibin, Vondriska Thomas M, Operationalizing Precision Cardiovascular Medicine: Three Innovations. Circulation research. 2016; 119(9): 984-987.
Wang Zhihua, Zhang Xiao-Jing, Ji Yan-Xiao, Zhang Peng, Deng Ke-Qiong, Gong Jun, Ren Shuxun, Wang Xinghua, Chen Iris, Wang He, Gao Chen, Yokota Tomohiro, Ang Yen Sin, Li Shen, Cass Ashley, Vondriska Thomas M, Li Guangping, Deb Arjun, Srivastava Deepak, Yang Huang-Tian, Xiao Xinshu, Li Hongliang, Wang Yibin, The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy. Nature medicine. 2016; 22(10): 1131-1139.
Rau, C. D.; Gao, C.; Wang, Y., Deconvolution of the Human Endothelial Transcriptome. Cell Syst. 2016; 3(3): 218-220.
Sun, H.; Wang, Y., Branched chain amino acid metabolic reprogramming in heart failure. Biochim Biophys Acta. 2016; .
Rau Christoph D, Gao Chen, Wang Yibin, Deconvolution of the Human Endothelial Transcriptome. Cell systems. 2016; 3(3): 218-220.
Karbassi Elaheh, Monte Emma, Chapski Douglas J, Lopez Rachel, Rosa Garrido Manuel, Kim Joseph, Wisniewski Nicholas, Rau Christoph D, Wang Jessica J, Weiss James N, Wang Yibin, Lusis Aldons J, Vondriska Thomas M, Relationship of disease-associated gene expression to cardiac phenotype is buffered by genetic diversity and chromatin regulation. Physiological genomics. 2016; 48(8): 601-15.
Karbassi, E.; Monte, E.; Chapski, D. J.; Lopez, R.; Rosa Garrido, M.; Kim, J.; Wisniewski, N.; Rau, C. D.; Wang, J. J.; Weiss, J. N.; Wang, Y.; Lusis, A. J.; Vondriska, T. M., Relationship of disease-associated gene expression to cardiac phenotype is buffered by genetic diversity and chromatin regulation. Physiol Genomics. 2016; 48(8): 601-15.
Monte, E.; Rosa-Garrido, M.; Karbassi, E.; Chen, H.; Lopez, R.; Rau, C. D.; Wang, J.; Nelson, S. F.; Wu, Y.; Stefani, E.; Lusis, A. J.; Wang, Y.; Kurdistani, S. K.; Franklin, S.; Vondriska, T. M., Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION. J Biol Chem. 2016; 291(30): 15428-46.
Wang Jessica Jen-Chu, Rau Christoph, Avetisyan Rozeta, Ren Shuxun, Romay Milagros C, Stolin Gabriel, Gong Ke Wei, Wang Yibin, Lusis Aldons J, Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. PLoS genetics. 2016; 12(7): e1006038.
Monte Emma, Rosa-Garrido Manuel, Karbassi Elaheh, Chen Haodong, Lopez Rachel, Rau Christoph D, Wang Jessica, Nelson Stanley F, Wu Yong, Stefani Enrico, Lusis Aldons J, Wang Yibin, Kurdistani Siavash K, Franklin Sarah, Vondriska Thomas M, Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION. The Journal of biological chemistry. 2016; 291(30): 15428-46.
Lusis Aldons J, Seldin Marcus M, Allayee Hooman, Bennett Brian J, Civelek Mete, Davis Richard C, Eskin Eleazar, Farber Charles R, Hui Simon, Mehrabian Margarete, Norheim Frode, Pan Calvin, Parks Brian, Rau Christoph D, Smith Desmond J, Vallim Thomas, Wang Yibin, Wang Jessica, The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits. Journal of lipid research. 2016; 57(6): 925-42.
Sun, H.; Olson, K. C.; Gao, C.; Prosdocimo, D. A.; Zhou, M.; Wang, Z.; Jeyaraj, D.; Youn, J. Y.; Ren, S.; Liu, Y.; Rau, C. D.; Shah, S.; Ilkayeva, O.; Gui, W. J.; William, N. S.; Wynn, R. M.; Newgard, C. B.; Cai, H.; Xiao, X.; Chuang, D. T.; Schulze, P. C.; Lynch, C.; Jain, M. K.; Wang, Y., Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure. Circulation. 2016; 133(21): 2038-49.
Sun Haipeng, Olson Kristine C, Gao Chen, Prosdocimo Domenick A, Zhou Meiyi, Wang Zhihua, Jeyaraj Darwin, Youn Ji-Youn, Ren Shuxun, Liu Yunxia, Rau Christoph D, Shah Svati, Ilkayeva Olga, Gui Wen-Jun, William Noelle S, Wynn R Max, Newgard Christopher B, Cai Hua, Xiao Xinshu, Chuang David T, Schulze Paul Christian, Lynch Christopher, Jain Mukesh K, Wang Yibin, Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure. Circulation. 2016; 133(21): 2038-49.
Gao Chen, Wang Yibin, Positive Role for a Negative Calcineurin Regulator in Cardiac Hypertrophy. Hypertension (Dallas, Tex. : 1979). 2016; 67(5): 841-2.
Cong, Q.; Jia, H.; Biswas, S.; Li, P.; Qiu, S.; Deng, Q.; Guo, X.; Ma, G.; Ling Chau, J. F.; Wang, Y.; Zhang, Z. L.; Jiang, X.; Liu, H.; Li, B., p38alpha MAPK Regulates Lineage Commitment and OPG Synthesis of Bone Marrow Stromal Cells to Prevent Bone Loss under Physiological and Pathological Conditions. Stem Cell Reports. 2016; 6(4): 566-78.
Cong Qian, Jia Hao, Biswas Soma, Li Ping, Qiu Shoutao, Deng Qi, Guo Xizhi, Ma Gang, Ling Chau Jenny Fang, Wang Yibin, Zhang Zhen-Lin, Jiang Xinquan, Liu Huijuan, Li Baojie, p38α MAPK Regulates Lineage Commitment and OPG Synthesis of Bone Marrow Stromal Cells to Prevent Bone Loss under Physiological and Pathological Conditions. Stem cell reports. 2016; 6(4): 566-78.
Chen, H.; Orozco, L. D.; Wang, J.; Rau, C. D.; Rubbi, L.; Ren, S.; Wang, Y.; Pellegrini, M.; Lusis, A. J.; Vondriska, T. M., DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States. Circ Res. 2016; 118(5): 786-97.
Chen Haodong, Orozco Luz D, Wang Jessica, Rau Christoph D, Rubbi Liudmilla, Ren Shuxun, Wang Yibin, Pellegrini Matteo, Lusis Aldons J, Vondriska Thomas M, DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States. Circulation research. 2016; 118(5): 786-97.
Iorga, A.; Li, J.; Sharma, S.; Umar, S.; Bopassa, J. C.; Nadadur, R. D.; Centala, A.; Ren, S.; Saito, T.; Toro, L.; Wang, Y.; Stefani, E.; Eghbali, M., Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy. J Am Heart Assoc. 2016; 5(1): .
Yokota, Tomohiro; Wang, Yibin, p38 MAP kinases in the heart. Gene. 2016; 575(2): 369-376.
Gao Chen, Ren Shuxun, Lee Jae-Hyung, Qiu Jinsong, Chapski Douglas J, Rau Christoph D, Zhou Yu, Abdellatif Maha, Nakano Astushi, Vondriska Thomas M, Xiao Xinshu, Fu Xiang-Dong, Chen Jau-Nian, Wang Yibin, RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure. The Journal of clinical investigation. 2016; 126(1): 195-206.
Iorga Andrea, Li Jingyuan, Sharma Salil, Umar Soban, Bopassa Jean C, Nadadur Rangarajan D, Centala Alexander, Ren Shuxun, Saito Tomoaki, Toro Ligia, Wang Yibin, Stefani Enrico, Eghbali Mansoureh, Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy. Journal of the American Heart Association. 2016; 5(1): 361-6.
Yokota Tomohiro, Wang Yibin, p38 MAP kinases in the heart. Gene. 2016; 575(2 Pt 2): 369-76.
Sun, H.; Wang, Y., The elusive philosopher's stone in young blood. Circ Res. 2015; 117(11): 906-8.
Feng Jiaying, Gong Danyang, Fu Xudong, Wu Ting-ting, Wang Jane, Chang Jennifer, Zhou Jingting, Lu Gang, Wang Yibin, Sun Ren, M1 of Murine Gamma-Herpesvirus 68 Induces Endoplasmic Reticulum Chaperone Production. Scientific reports. 2015; 5(52): 17228.
Sun Haipeng, Wang Yibin, The elusive philosopher's stone in young blood. Circulation research. 2015; 117(11): 906-8.
Cattin, M. E.; Wang, J.; Weldrick, J. J.; Roeske, C. L.; Mak, E.; Thorn, S. L.; DaSilva, J. N.; Wang, Y.; Lusis, A. J.; Burgon, P. G., Deletion of MLIP (Muscle-enriched A-type Lamin-interacting Protein) Leads to Cardiac Hyperactivation of Akt/Mammalian Target of Rapamycin (mTOR) and Impaired Cardiac Adaptation. J Biol Chem. 2015; 290(44): 26699-714.
Cattin Marie-Elodie, Wang Jessica, Weldrick Jonathan J, Roeske Cassandra L, Mak Esther, Thorn Stephanie L, DaSilva Jean N, Wang Yibin, Lusis Aldon J, Burgon Patrick G, Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptation. The Journal of biological chemistry. 2015; 290(44): 26699-714.
Neelankavil Jacques, Rau Christoph D, Wang Yibin, The Genetic Basis of Coronary Artery Disease and Atrial Fibrillation: A Search for Disease Mechanisms and Therapeutic Targets. Journal of cardiothoracic and vascular anesthesia. 2015; 29(5): 1328-32.
Sun, H.; Gao, C.; Wang, Y., A H(a)rd Way to Adapt in Cardiac Hypertrophy. Circ Res. 2015; 117(6): 484-6.
Sun Haipeng, Gao Chen, Wang Yibin, A H(a)rd Way to Adapt in Cardiac Hypertrophy. Circulation research. 2015; 117(6): 484-6.
Song Yang, Zhang Yonghong, Jiang Haoxiang, Zhu Yanting, Liu Lu, Feng Wei, Yang Lan, Wang Yibin, Li Manxiang, Activation of Notch3 promotes pulmonary arterial smooth muscle cells proliferation via Hes1/p27Kip1 signaling pathway. FEBS open bio. 2015; 5(6): 656-60.
Rau Christoph D, Parks Brian, Wang Yibin, Eskin Eleazar, Simecek Petr, Churchill Gary A, Lusis Aldons J, High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. G3 (Bethesda, Md.). 2015; 5(10): 2021-6.
Rau Christoph D, Lusis Aldons J, Wang Yibin, Genetics of common forms of heart failure: challenges and potential solutions. Current opinion in cardiology. 2015; 30(3): 222-7.
Deb, A.; Wang, Y., Hypertrophic preconditioning: short-term tricks for long-term gain. Circulation. 2015; 131(17): 1468-70.
Deb Arjun, Wang Yibin, Hypertrophic preconditioning: short-term tricks for long-term gain. Circulation. 2015; 131(17): 1468-70.
Cai Rong, Gu Jianmin, Sun Haipeng, Liu Xiaobing, Mei Wenhan, Qi Yitao, Xue Song, Ren Shuxun, Rabinowitz Joseph E, Wang Yibin, Yeh Edward T H, Cheng Jinke, Induction of SENP1 in myocardium contributes to abnormities of mitochondria and cardiomyopathy. Journal of molecular and cellular cardiology. 2015; 79(1): 115-22.
Rau Christoph D, Wang Jessica, Avetisyan Rozeta, Romay Milagros C, Martin Lisa, Ren Shuxun, Wang Yibin, Lusis Aldons J, Mapping genetic contributions to cardiac pathology induced by Beta-adrenergic stimulation in mice. Circulation. Cardiovascular genetics. 2015; 8(1): 40-9.
Wang, Z.; Wang, Y., Dawn of the Epi-LncRNAs: new path from Myheart. Circ Res. 2015; 116(2): 235-6.
Wang Zhihua, Wang Yibin, Dawn of the Epi-LncRNAs: new path from Myheart. Circulation research. 2015; 116(2): 235-6.
Briot, A.; Jaroszewicz, A.; Warren, C. M.; Lu, J.; Touma, M.; Rudat, C.; Hofmann, J. J.; Airik, R.; Weinmaster, G.; Lyons, K.; Wang, Y.; Kispert, A.; Pellegrini, M.; Iruela-Arispe, M. L., Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Dev Cell. 2014; 31(6): 707-21.
Ren Shuxun, Lu Gang, Ota Asuka, Zhou Z Hong, Vondriska Thomas M, Lane Timothy F, Wang Yibin, IRE1 phosphatase PP2Ce regulates adaptive ER stress response in the postpartum mammary gland. PloS one. 2014; 9(11): e111606.
Briot Anaïs, Jaroszewicz Artur, Warren Carmen M, Lu Jing, Touma Marlin, Rudat Carsten, Hofmann Jennifer J, Airik Rannar, Weinmaster Gerry, Lyons Karen, Wang Yibin, Kispert Andreas, Pellegrini Matteo, Iruela-Arispe M Luisa, Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Developmental cell. 2014; 31(6): 707-21.
Sun Haipeng, Wang Yibin, Interferon regulatory factors in heart: stress response beyond inflammation. Hypertension (Dallas, Tex. : 1979). 2014; 63(4): 663-4.
Lam Maggie P Y, Wang Ding, Lau Edward, Liem David A, Kim Allen K, Ng Dominic C M, Liang Xiangbo, Bleakley Brian J, Liu Chenguang, Tabaraki Jason D, Cadeiras Martin, Wang Yibin, Deng Mario C, Ping Peipei, Protein kinetic signatures of the remodeling heart following isoproterenol stimulation. The Journal of clinical investigation. 2014; 124(4): 1734-44.
Wang, Y., Blind dates in sciences: dealing with rejection in peer review. Circ Res. 2014; 114(6): 944-6.
Xiao, X. G.; Touma, M.; Wang, Y., Decoding the noncoding transcripts in human heart failure. Circulation. 2014; 129(9): 958-60.
Wang Yibin, Blind dates in sciences: dealing with rejection in peer review. Circulation research. 2014; 114(6): 944-6.
Xiao Xinshu Grace, Touma Marlin, Wang Yibin, Decoding the noncoding transcripts in human heart failure. Circulation. 2014; 129(9): 958-60.
Gao Chen, Wang Yibin, Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome. Circulation journal : official journal of the Japanese Circulation Society. 2014; 78(5): 1038-47.
Gupta Ashish, Rohlfsen Cory, Leppo Michelle K, Chacko Vadappuram P, Wang Yibin, Steenbergen Charles, Weiss Robert G, Creatine kinase-overexpression improves myocardial energetics, contractile dysfunction and survival in murine doxorubicin cardiotoxicity. PloS one. 2013; 8(10): e74675.
Monte Emma, Mouillesseaux Kevin, Chen Haodong, Kimball Todd, Ren Shuxun, Wang Yibin, Chen Jau-Nian, Vondriska Thomas M, Franklin Sarah, Systems proteomics of cardiac chromatin identifies nucleolin as a regulator of growth and cellular plasticity in cardiomyocytes. American journal of physiology. Heart and circulatory physiology. 2013; 305(11): H1624-38.
Monte, E.; Mouillesseaux, K.; Chen, H.; Kimball, T.; Ren, S.; Wang, Y.; Chen, J. N.; Vondriska, T. M.; Franklin, S., Systems proteomics of cardiac chromatin identifies nucleolin as a regulator of growth and cellular plasticity in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2013; 305(11): H1624-38.
Foster William H, Langenbacher Adam, Gao Chen, Chen Jaunian, Wang Yibin, Nuclear phosphatase PPM1G in cellular survival and neural development. Developmental dynamics : an official publication of the American Association of Anatomists. 2013; 242(9): 1101-9.
Lu Gang, Ota Asuka, Ren Shuxun, Franklin Sarah, Rau Christoph D, Ping Peipei, Lane Timothy F, Zhou Z Hong, Reue Karen, Lusis Aldons J, Vondriska Thomas, Wang Yibin, PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response. Molecular metabolism. 2013; 2(4): 405-16.
Force, T.; Wang, Y., Mechanism-based engineering against anthracycline cardiotoxicity. Circulation. 2013; 128(2): 98-100.
Force Thomas, Wang Yibin, Mechanism-based engineering against anthracycline cardiotoxicity. Circulation. 2013; 128(2): 98-100.
Ahuja, P.; Wanagat, J.; Wang, Z.; Wang, Y.; Liem, D. A.; Ping, P.; Antoshechkin, I. A.; Margulies, K. B.; Maclellan, W. R., Divergent mitochondrial biogenesis responses in human cardiomyopathy. Circulation. 2013; 127(19): 1957-67.
Ahuja Preeti, Wanagat Jonathan, Wang Zhihua, Wang Yibin, Liem David A, Ping Peipei, Antoshechkin Igor A, Margulies Kenneth B, Maclellan W Robb, Divergent mitochondrial biogenesis responses in human cardiomyopathy. Circulation. 2013; 127(19): 1957-67.
Hofmann Jennifer J, Briot Anais, Enciso Josephine, Zovein Ann C, Ren Shuxun, Zhang Zhen W, Radtke Freddy, Simons Michael, Wang Yibin, Iruela-Arispe M Luisa, Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome. Development (Cambridge, England). 2012; 139(23): 4449-60.
Hofmann, J. J.; Briot, A.; Enciso, J.; Zovein, A. C.; Ren, S.; Zhang, Z. W.; Radtke, F.; Simons, M.; Wang, Y.; Iruela-Arispe, M. L., Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome. Development. 2012; 139(23): 4449-60.
Hajjar, R. J.; Leri, A.; Wang, Y., BCVS scientific conference 2012 meeting report. Circ Res. 2012; 111(9): 1121-4.
Hajjar Roger J, Leri Annarosa, Wang Yibin, BCVS scientific conference 2012 meeting report. Circulation research. 2012; 111(9): 1121-4.
Akki, A.; Su, J.; Yano, T.; Gupta, A.; Wang, Y.; Leppo, M. K.; Chacko, V. P.; Steenbergen, C.; Weiss, R. G., Creatine kinase overexpression improves ATP kinetics and contractile function in postischemic myocardium. Am J Physiol Heart Circ Physiol. 2012; 303(7): H844-52.
Weiss, J. N.; Karma, A.; MacLellan, W. R.; Deng, M.; Rau, C. D.; Rees, C. M.; Wang, J.; Wisniewski, N.; Eskin, E.; Horvath, S.; Qu, Z.; Wang, Y.; Lusis, A. J., "Good enough solutions" and the genetics of complex diseases. Circ Res. 2012; 111(4): 493-504.
Weiss James N, Karma Alain, MacLellan W Robb, Deng Mario, Rau Christoph D, Rees Colin M, Wang Jessica, Wisniewski Nicholas, Eskin Eleazar, Horvath Steve, Qu Zhilin, Wang Yibin, Lusis Aldons J, "Good enough solutions" and the genetics of complex diseases. Circulation research. 2012; 111(4): 493-504.
Gao Chen, Wang Yibin, Global impact of RNA splicing on transcriptome remodeling in the heart. Journal of Zhejiang University. Science. B. 2012; 13(8): 603-8.
Zhou, M.; Lu, G.; Gao, C.; Wang, Y.; Sun, H., Tissue-specific and nutrient regulation of the branched-chain alpha-keto acid dehydrogenase phosphatase, protein phosphatase 2Cm (PP2Cm). J Biol Chem. 2012; 287(28): 23397-406.
Zhou Meiyi, Lu Gang, Gao Chen, Wang Yibin, Sun Haipeng, Tissue-specific and nutrient regulation of the branched-chain α-keto acid dehydrogenase phosphatase, protein phosphatase 2Cm (PP2Cm). The Journal of biological chemistry. 2012; 287(28): 23397-406.
Sun, H.; Wang, Y., Prostaglandin E2 in remote control of myocardial remodeling. Circulation. 2012; 125(23): 2818-20.
Sun Haipeng, Wang Yibin, Prostaglandin E2 in remote control of myocardial remodeling. Circulation. 2012; 125(23): 2818-20.
Franklin Sarah, Chen Haodong, Mitchell-Jordan Scherise, Ren Shuxun, Wang Yibin, Vondriska Thomas M, Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth. Molecular & cellular proteomics : MCP. 2012; 11(6): M111.014258.
Jeyaraj, D.; Scheer, F. A.; Ripperger, J. A.; Haldar, S. M.; Lu, Y.; Prosdocimo, D. A.; Eapen, S. J.; Eapen, B. L.; Cui, Y.; Mahabeleshwar, G. H.; Lee, H. G.; Smith, M. A.; Casadesus, G.; Mintz, E. M.; Sun, H.; Wang, Y.; Ramsey, K. M.; Bass, J.; Shea, S. A.; Albrecht, U.; Jain, M. K., Klf15 orchestrates circadian nitrogen homeostasis. Cell Metab. 2012; 15(3): 311-23.
Ota, A.; Wang, Y., Cdc37/Hsp90 protein-mediated regulation of IRE1alpha protein activity in endoplasmic reticulum stress response and insulin synthesis in INS-1 cells. J Biol Chem. 2012; 287(9): 6266-74.
Zhu, W.; Petrashevskaya, N.; Ren, S.; Zhao, A.; Chakir, K.; Gao, E.; Chuprun, J. K.; Wang, Y.; Talan, M.; Dorn, G. W., 2nd; Lakatta, E. G.; Koch, W. J.; Feldman, A. M.; Xiao, R. P., Gi-biased beta2AR signaling links GRK2 upregulation to heart failure. Circ Res. 2012; 110(2): 265-74.
Gupta, A.; Akki, A.; Wang, Y.; Leppo, M. K.; Chacko, V. P.; Foster, D. B.; Caceres, V.; Shi, S.; Kirk, J. A.; Su, J.; Lai, S.; Paolocci, N.; Steenbergen, C.; Gerstenblith, G.; Weiss, R. G., Creatine kinase-mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved. J Clin Invest. 2012; 122(1): 291-302.
Lee, J. H.; Gao, C.; Peng, G.; Greer, C.; Ren, S.; Wang, Y.; Xiao, X., Analysis of transcriptome complexity through RNA sequencing in normal and failing murine hearts. Circ Res. 2011; 109(12): 1332-41.
Korge, P.; Yang, L.; Yang, J. H.; Wang, Y.; Qu, Z.; Weiss, J. N., Protective role of transient pore openings in calcium handling by cardiac mitochondria. J Biol Chem. 2011; 286(40): 34851-7.
Huang, Y.; Zhou, M.; Sun, H.; Wang, Y., Branched-chain amino acid metabolism in heart disease: an epiphenomenon or a real culprit?. Cardiovasc Res. 2011; 90(2): 220-3.
Sun, H.; Wang, Y., Restriction of big hearts by a small RNA. Circ Res. 2011; 108(3): 274-6.
Yang, S. H.; Chang, S. Y.; Ren, S.; Wang, Y.; Andres, D. A.; Spielmann, H. P.; Fong, L. G.; Young, S. G., Absence of progeria-like disease phenotypes in knock-in mice expressing a non-farnesylated version of progerin. Hum Mol Genet. 2011; 20(3): 436-44.
Zhang, M.; Takimoto, E.; Hsu, S.; Lee, D. I.; Nagayama, T.; Danner, T.; Koitabashi, N.; Barth, A. S.; Bedja, D.; Gabrielson, K. L.; Wang, Y.; Kass, D. A., Myocardial remodeling is controlled by myocyte-targeted gene regulation of phosphodiesterase type 5. J Am Coll Cardiol. 2010; 56(24): 2021-30.
Fung, A. O.; Tsiokos, C.; Paydar, O.; Chen, L. H.; Jin, S.; Wang, Y.; Judy, J. W., Electrochemical properties and myocyte interaction of carbon nanotube microelectrodes. Nano Lett. 2010; 10(11): 4321-7.
Drews, O.; Tsukamoto, O.; Liem, D.; Streicher, J.; Wang, Y.; Ping, P., Differential regulation of proteasome function in isoproterenol-induced cardiac hypertrophy. Circ Res. 2010; 107(9): 1094-101.
Davies, B. S.; Barnes, R. H., 2nd; Tu, Y.; Ren, S.; Andres, D. A.; Spielmann, H. P.; Lammerding, J.; Wang, Y.; Young, S. G.; Fong, L. G., An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria. Hum Mol Genet. 2010; 19(13): 2682-94.
Streicher, J. M.; Ren, S.; Herschman, H.; Wang, Y., MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart. Circ Res. 2010; 106(8): 1434-43.
Ota, A.; Zhang, J.; Ping, P.; Han, J.; Wang, Y., Specific regulation of noncanonical p38alpha activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte. Circ Res. 2010; 106(8): 1404-12.
Sun, Y.; Ishibashi, M.; Seimon, T.; Lee, M.; Sharma, S. M.; Fitzgerald, K. A.; Samokhin, A. O.; Wang, Y.; Sayers, S.; Aikawa, M.; Jerome, W. G.; Ostrowski, M. C.; Bromme, D.; Libby, P.; Tabas, I. A.; Welch, C. L.; Tall, A. R., Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K. Circ Res. 2009; 104(4): 455-65.
Mitchell-Jordan, S. A.; Holopainen, T.; Ren, S.; Wang, S.; Warburton, S.; Zhang, M. J.; Alitalo, K.; Wang, Y.; Vondriska, T. M., Loss of Bmx nonreceptor tyrosine kinase prevents pressure overload-induced cardiac hypertrophy. Circ Res. 2008; 103(12): 1359-62.
Vondriska, T. M.; Wang, Y., A new (heat) shocking player in cardiac hypertrophy. Circ Res. 2008; 103(11): 1194-6.
Kang, Y. J.; Chen, J.; Otsuka, M.; Mols, J.; Ren, S.; Wang, Y.; Han, J., Macrophage deletion of p38alpha partially impairs lipopolysaccharide-induced cellular activation. J Immunol. 2008; 180(7): 5075-82.
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