Directory

Alan Grinnell, Ph.D. [ Edit Your Profile ]

Email Address: adg@ucla.edu

Lab Number: (310) 825-7870
Office Phone Number: 310-825-4468

Work Address:
CHS
Los Angeles, CA 90095 Dept. of Physiology,
David Geffen School of Medicine at UCLA
Los Angeles, CA 90095

Work
Position/Title
Distinguished Professor, Integrative Biology and Physiology
Professor, Physiology
Associate Dean, Life Sciences
Member, Brain Research Institute, Cell & Developmental Biology GPB Home Area, Center for Duchenne Muscular Dystrophy, Molecular, Cellular & Integrative Physiology GPB Home Area

Education:
Degrees:
Ph.D.

Publications
Yazejian Bruce, Yazejian Rita M, Einarsson Rachel, Grinnell Alan D, Simultaneous pre- and post-synaptic electrophysiological recording from Xenopus nerve-muscle co-cultures. Journal of visualized experiments : JoVE. 2013; (73): e50253.
Kim Michelle H, Kay Danielle I, Rudra Renuka T, Chen Bo Ming, Hsu Nigel, Izumiya Yasuhiro, Martinez Leonel, Spencer Melissa J, Walsh Kenneth, Grinnell Alan D, Crosbie Rachelle H, Myogenic Akt signaling attenuates muscular degeneration, promotes myofiber regeneration and improves muscle function in dystrophin-deficient mdx mice. Human molecular genetics. 2011; 20(7): 1324-38.
Sun Xiao-Ping, Chen Bo-Ming, Sand Olav, Kidokoro Yoshi, Grinnell Alan D, Depolarization-induced Ca2+ entry preferentially evokes release of large quanta in the developing Xenopus neuromuscular junction. Journal of neurophysiology. 2010; 104(5): 2730-40.
Grinnell, A.D., Echolocation I: Behavior. New Encyclopedia of Neuroscience, ed. L. R. Squire, in press,. 2007; .
Grinnell, A.D., How Muscle Stretch In fluences Neuromuscular Transmission, ed. L. R. Squire, in press. New Encyclopedia of Neuroscience. 2007; .
Sun, X-P, Yazejian, B. and Grinnell, A.D., Electrophysiological properties of BK channels in Xenopus motor nerve terminals. J. Physiol. 2004; 557: 207-228.
Sun, XP Yazejian, B Grinnell, AD, Electrophysiological properties of BK channels in Xenopus motor nerve terminals. The Journal of physiology. . 2004; 557(Pt 1): 207-28.
Sun Xiao-Ping, Yazejian Bruce, Grinnell Alan D, Electrophysiological properties of BK channels in Xenopus motor nerve terminals. The Journal of physiology. 2004; 557(Pt 1): 207-28.
Grinnell Alan D, Chen Bo-Ming, Kashani Amir, Lin Jennifer, Suzuki Kazuhiro, Kidokoro Yoshiaki, The role of integrins in the modulation of neurotransmitter release from motor nerve terminals by stretch and hypertonicity. Journal of neurocytology. 2004; 32(5-8): 489-503.
Grinnell, A.D., Chen, B.-M., Kashani, A., Lin, J., Suzuki, K., and Kidokoro, Y., The role of integrins in the modulation of neurotransmitter release from motor nerve terminals by stretch and hypertonicity. J. Neurocytol. 2003; 32: 489-503.
Suzuki, K Grinnell, AD Kidokoro, Y, Hypertonicity-induced transmitter release at Drosophila neuromuscular junctions is partly mediated by integrins and cAMP/protein kinase A. The Journal of physiology. . 2002; 538(Pt 1): 103-19.
Sand, O Chen, BM Grinnell, AD, Contribution of L-type Ca(2+) channels to evoked transmitter release in cultured Xenopus nerve-muscle synapses. The Journal of physiology. . 2001; 536(Pt 1): 21-33.
Kashani, A., Chen, B.-M., and Grinnell, Osmotic modulation of transmitter release from frog motor nerve terminals: Ca++-independence and role of integrins. J. Physiol. 2001; 530: 243-252.
Yazejian, B, Sun, X.-P, and Grinnell, A.D., Tracking presynaptic Ca++ dynamics during neurotransmitter release with Ca-activated K+ channels. Nature Neuroscience. 2000; 3: 566-571.
Kalko, E.K.V., Schnitzler, H.-U., Kaipf, I & Grinnell, A.D., Hunting and echolocation behavior in Noctilio albiventris: the evolution of piscivory. Behavioral Ecology and Sociobiology. 1998; 45: 305-319.
Chen, B.M and Grinnell, A.D., Kinetics, Ca++ dependence, and biophysical properties of integrin-mediated mechanical modulation of transmitter release from frog motor nerve terminals. J. Neuroscience. 1997; 17: 904-916.
Yazejian, B DiGregorio, DA Vergara, JL Poage, RE Meriney, SD Grinnell, AD, Direct measurements of presynaptic calcium and calcium-activated potassium currents regulating neurotransmitter release at cultured Xenopus nerve-muscle synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. . 1997; 17(9): 2990-3001.
Harada, Y Grinnell, AD, Regeneration of specific innervation in Xenopus pectoralis muscle. Journal of neurobiology. . 1996; 31(4): 433-48.
Grinnell, AD Harada, Y, Specificity and development of innervation pattern of Xenopus pectoralis muscle. Journal of neurobiology. . 1996; 31(4): 415-32.
Grinnell, AD, Dynamics of nerve-muscle interaction in developing and mature neuromuscular junctions. Physiological reviews. . 1995; 75(4): 789-834.
Chen, B.M. and Grinnell, A.D., Integrins help mediate the stretch-induced modulation of transmitter release from frog motor nerve terminals. Science. 1995; 269: 1578-1580.